Food and Epigenetics: How Polyphenols Talk to Our DNA
Eating is not just about nourishment: it’s about dialogue with our epigenome. Recent studies show that diets rich in polyphenols – compounds found in green tea, berries, nuts, olives, herbs, and leafy vegetables – can slow down the advance of “epigenetic age,” measured with molecular clocks that track DNA methylation. In an 18-month trial, a “green” version of the Mediterranean diet reduced the accumulation of epigenetic marks linked to aging, with benefits also observed in metabolism and inflammatory markers.
The mechanism works through the microbiome: polyphenols are transformed by gut bacteria into metabolites that act on DNA, modulate epigenetic enzymes, and reduce chronic inflammation. This means that the very same diet can have different effects depending on each person’s intestinal flora. It is not food alone that makes the difference, but the synergy with our inner ecosystem.
In daily practice, extreme diets are not necessary: simply increasing the intake of polyphenol-rich foods such as fruit, leafy greens, spices, green tea, and nuts every day produces dose-dependent effects. Anti-aging is not about a miracle pill, but the steady accumulation of small, consistent choices.
Unexpected conclusion: the next anti-aging revolution may start at the grocery store, not at the pharmacy. It’s not about chasing the latest supplement, but realizing that a dish prepared with leaves, berries, and spices is both an epigenetic act and, ultimately, a spiritual gesture.
The mechanism works through the microbiome: polyphenols are transformed by gut bacteria into metabolites that act on DNA, modulate epigenetic enzymes, and reduce chronic inflammation. This means that the very same diet can have different effects depending on each person’s intestinal flora. It is not food alone that makes the difference, but the synergy with our inner ecosystem.
In daily practice, extreme diets are not necessary: simply increasing the intake of polyphenol-rich foods such as fruit, leafy greens, spices, green tea, and nuts every day produces dose-dependent effects. Anti-aging is not about a miracle pill, but the steady accumulation of small, consistent choices.
Unexpected conclusion: the next anti-aging revolution may start at the grocery store, not at the pharmacy. It’s not about chasing the latest supplement, but realizing that a dish prepared with leaves, berries, and spices is both an epigenetic act and, ultimately, a spiritual gesture.